Sr. Associate ScientistRare Neurodevelopmental Disease
Company: Sanofi
Location: Cambridge
Posted on: April 2, 2026
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Job Description:
Job Title : Sr. Associate ScientistRare Neurodevelopmental
Disease Location: Cambridge, MA About the Job We are seeking a
meticulous, dynamin and team-oriented individual to join our Rare
Neurodevelopmental Disease Team in Sanofis Rare Disease Therapeutic
Area group. In this position, the individual will support efforts
to characterize and develop preclinical molecules or biologics as
well as disease models (cells and animals) aimed at treating
patients with rare diseases. Duties will include a broad range of
in vitro and in vivo techniques as well as the execution of
established assays to better understand the various emerging
modalities currently in pre-clinic stage to treat rare
neurodevelopmental diseases. We are committed to advancing the
understanding of disease mechanisms and translating these insights
into meaningful therapeutic solutions for patients with rare
monogenic neurodevelopmental disorders. Are you ready to shape the
future of medicine? The race is on to speed up drug discovery and
development to find answers for patients and their families. Your
skills could be critical in helping our teams accelerate progress.
About Sanofi: Were an R&D-driven, AI-powered biopharma company
committed to improving peoples lives and delivering compelling
growth. Our deep understanding of the immune system and innovative
pipeline enables us to invent medicines and vaccines that treat and
protect millions of people around the world. Together, we chase the
miracles of science to improve peoples lives. Main
Responsibilities: Perform experiments and studies in support of
rare disease research projects and company drug discovery goals.
Design, execute, and troubleshoot experiments in both in vivo and
in vitro settings. Support the development of new methodologies and
approaches as needed. Conduct of a broad range of established in
vivo techniques including handling mice, IV, IP, SC and ICV
injections, anesthesia, necropsy, collection of mouse tissues as
well as behavior, cognitive and motor functional assays (treadmill,
rotarod, grip strength, elevated plus maze assay, open field,
marbles burying assay) and Electroencephalogram (EEG). Execute a
broad range of in vitro protocols including culturing human and
mouse cells, cell transfection, RNA extraction, RT-qPCR, analysis,
Western blots, ELISA, plate-based assay (MSD). Analyze, interpret,
and present experimental results to team members and project
stakeholders. Maintain detailed and accurate laboratory records
following scientific rigor standards. Demonstrated ability to work
in a team environment and collaborate effectively. Strong
analytical and problem-solving abilities. Ability to prioritize and
organize work to meet project deadlines. Knowledge of laboratory
safety procedures and good laboratory practices. Adapting to
various workflows with the flexibility to change directions and
work on a broad range of scientific problems. About you Basic
Qualifications: Bachelor's Degree plus minimum 4 years of relevant
research experience in an academic or biopharmaceutical setting OR
Master's Degree plus minimum 1 year of relevant research
experience. Strong in vivo technical expertise including animal
handling, various routes of administration (IV, SC, IP, ICV),
anesthesia, and necropsy. Experience with in vivo models of rare
neurodevelopmental disorders and associated functional readouts.
Proficiency in cell culture techniques, including iPSC culture
systems. Demonstrated ability to work in a team environment and
collaborate effectively. Excellent documentation and record-keeping
skills. Strong analytical and problem-solving abilities. Ability to
prioritize and organize work to meet project deadlines. Knowledge
of laboratory safety procedures and good laboratory practices.
Preferred Qualifications Experience with transfection of several
types of cell lines. Experience with RNA handling and downstream
analysis (RNA extraction, RT-qPCR) Experience with protein handling
(ELISA/MSD, assays, pull-downs, Westerns, etc.). Experience with
high-throughput screening and assay development. Experience
integrating human biology datasets (e.g., genomics,
transcriptomics) into experimental workflows. Familiarity with
bioinformatics tools and data analysis software. Previous
experience in pharmaceutical or biotechnology research settings.
Why Choose Us Bring the miracles of science to life alongside a
supportive, future-focused team. Discover endless opportunities to
grow your talent and drive your career, whether its through a
promotion or lateral move, at home or internationally. Enjoy a
thoughtful, well-crafted rewards package that recognizes your
contribution and amplifies your impact. Take good care of yourself
and your family, with a wide range of health and wellbeing benefits
including high-quality healthcare, prevention and wellness programs
and at least 14 weeks gender-neutral parental leave. Be part of a
pioneering biopharma company that engages patients early in drug
development and uses their insights to design studies that reflect
real-world needs. Help improve the lives of millions of people
globally by making drug development quicker and more effective.
Work at the forefront of drug discovery, harnessing cutting-edge
AI, data, and digital platforms to push the boundaries of science.
Sanofi Inc. and its U.S. affiliates are Equal Opportunity and
Affirmative Action employers committed to a culturally diverse
workforce. All qualified applicants will receive consideration for
employment without regard to race; color; creed; religion; national
origin; age; ancestry; nationality; marital, domestic partnership
or civil union status; sex, gender, gender identity or expression;
affectional or sexual orientation; disability; veteran or military
status or liability for military status; domestic violence victim
status; atypical cellular or blood trait; genetic information
(including the refusal to submit to genetic testing) or any other
characteristic protected by law. GD-SA LI-SA LI-Onsite vhd All
compensation will be determined commensurate with demonstrated
experience. Employees may be eligible to participate in Company
employee benefit programs, and additional benefits information can
be found here.
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